Recent publications
Kawai-Harada, Y, Mardikoraem M, Makela AV, Lauro K, Lam J, Contag CH, Woldring D, Harada M. VesicleVoyager: In vivo selection of surface displayed proteins that direct extracellular vesicles to tissue-specific targets. J. Extracell. Vesicles 2025;1(1), 9, doi.org/10.1002/jev2.70184
Kawai-Harada, Y, Nimmagadda, V, Harada M. Scalable isolation of surface-engineered extracellular vesicles and separation of free proteins via tangential flow filtration and size exclusion chromatography (TFF-SEC). BMC Methods 2024;1(1), 9, doi.org/10.1186/s44330-024-00009-0
Kawai-Harada, Y, El Itawi, H, Komuro, H, Harada M. Evaluation of EV Storage Buffer for Efficient Preservation of Engineered Extracellular Vesicles. Int J Mol Sci 2023;24, doi:10.3390/ijms241612841
Komuro H, Aminova S, Lauro K, Woldring D, Harada M. Design and Evaluation of Engineered Extracellular Vesicle (EV)-Based Targeting for EGFR-Overexpressing Tumor Cells Using Monobody Display. Bioengineering 2022, 9(2), 56. doi: 10.3390/bioengineering9020056. NEW!
Komuro H, Kawai-Harada Y, Aminova S, Pascual N, Malik A, Contag CH, Harada M. Engineering Extracellular Vesicles to Target Pancreatic Tissue In Vivo. Nanotheranostics 2021; 5(4):378-390. doi: 10.7150/ntno.54879.
Forterre A, Komuro H, Aminova S, Harada M. A Comprehensive Review of Cancer MicroRNA Therapeutic Delivery Strategies. Cancers (2020) 12(7). DOI: 10.3390/cancers12071852
Wang P, Kim T, Harada M, Contag C, Huang X, Smith BR. Nano-immunoimaging. Nanoscale Horiz. (2020) 5(4):628-653. DOI: 10.1039/C9NH00514E
Lohcharoenkal W, Harada M, Lovén J, Meisgen F, Landén NX, Zhang L, Lapins J, Mahapatra KD, Shi H, Nissinen L, Kähäri VM, Ståhle M, Sonkoly E, Grandér D, Arsenian-Henriksson M, Pivarcsi A., MicroRNA-203 Inversely Correlates with Differentiation Grade, Targets c-MYC, and Functions as a Tumor Suppressor in cSCC. J Invest Dermatol (2016) 136(12):2485-2494. DOI: 10.1016/j.jid.2016.06.630
Harada M., Benito, J., Yamamoto, S., Kaur, S., Arslan, D., Ramirez, S., Jacamo, R., Platanias, L., Matsushita, H., Fujimura, T., Kazuno, S., Kojima, K., Tabe, Y., Konopleva, M., The novel combination of dual mTOR inhibitor AZD2014 and pan-PIM inhibitor AZD1208 inhibits growth in acute myeloid leukemia via HSF pathway suppression. Oncotarget (2015) Nov 10;6(35):37930-47 DOI: 10.18632/oncotarget.6122
Xu N, Zhang L, Meisgen F, Harada M, Heilborn J, Homey B, Grander D, Stahle M, Sonkoly E, Pivarcsi A., MicroRNA-125b Down-regulates Matrix Metallopeptidase 13 and Inhibits Cutaneous Squamous Cell Carcinoma Cell Proliferation, Migration and Invasion. J Biol Chem. (2012) Jul 10 DOI: 10.1074/jbc.M112.391243
Harada M, Pokrovskaja Tamm K, Soderhall S, Heyman M, Grander D, et al. Involvement of the miR17 pathway in glucocorticoid-induced cell death in pediatric acute lymphoblastic leukemia. Leuk Lymphoma. (2012) DOI: 10.3109/10428194.2012.678004